Volume 13 Issue 8
Pulmonary Embolism: Progress in Diagnosis, Clinical Presentation, and Management
1Hub e Ali, 2Zamin Abbas, 3Ahmed Haroon, 4Danish Marwat, 5Asad Jahangir, 6Mirza Muhammad Ayub Baig
1Gangaram Hospital, Lahore
2Mayo Hospital, Lahore
3Service Hospital, Lahore
4PIMS, Islamabad
5UHS, Lahore
6Jinnah Hospital, Lahore
Abstract
Background
Pulmonary embolism is a condition of dangerous obstruction of the pulmonary arteries, primarily by thromboembolism from deep vein thrombosis. Correct early diagnosis and proper management are necessary to prohibit morbidity and mortality.
Objectives:
The present study contrast diagnostic methods, clinical presentations, and outcomes of pulmonary embolism patients, highlighting imaging and anticoagulation as keys to management.
Methods:
A prospective cohort study was performed on 200 patients suspected of having PE. The diagnosis was established by computed tomography pulmonary angiography, ventilation-perfusion scan, and D-dimer testing. The treatment modality, such as anticoagulation, thrombolysis, and supportive care, was evaluated.
Results:
CTPA diagnosed PE in 140 patients (70%). In confirmed cases, elevated D-dimer had significant correlation. Anticoagulation was the initial mode of management; thrombolysis was reserved for high-risk patients. Survival was better with early diagnosis and prompt initiation of therapy.
Conclusions:
Pulmonary embolism continues to be a challenge in diagnosis and treatment. Imaging and biomarker-guided strategies improve early detection, and anticoagulation continues to be the mainstay of therapy. Early intervention is better and decreases the risk of recurrence.
Keywords: Pulmonary, anticoagulation, Angiography